The upper portion of the coat of arms is symbolic of the Immaculate Heart of Mary, the patroness of the diocese. This dedication is represented by a field of blue, the traditional color of the Blessed Virgin Mary, upon which is emblazoned a silver heart and a heraldic rose, Beneath this is a silver crescent, indicating the Immaculate Conception.
Immediately below the upper portion is another section, or brusure, on which is found the arms of the Von Steuben family, which was used by Baron Von Steuben, after whom the city is named, as his personal arms. This, of course, indicates the City of Steubenville. This field is halved into silver and blue, with a diagonal stripe, of bend in red.
In the lower section, red Pentecostal tongues of fire on a silver field refer to the Church's mission. This symbol is from the Gospel of Luke, Chapter 12, Verse 49: “I have come to set the earth on fire, and how I wish it were already blazing!" Holy Name Cathedral is indicated by a heraldic "celestial crown" of gold, surmounted by seven stars, and resting on a field of red. The IHS, ecclesiastical symbol for the name of Jesus, in engraved on the crown.